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  • 河北科技師范學院

    學術活動

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    學術活動
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    正文
    學術預告/海洋活性多糖/寡糖的發掘與利用
    【發布日期: 2019-06-18】 【發布單位: 】 【供稿人:】

    主講人:張全斌

    活動時間:6月21日9:00

    活動地點:老樓三樓工會會議室

    組織單位:分析測試中心、海洋科學研究院

    講座內容:

        海洋生物適應高鹽、開放的海洋環境,能夠合成結構獨特的活性成分,特別是結構特殊的硫酸化多糖。課題組通過對海洋多糖/寡糖的系統研究,發現了多個具有顯著藥理活性的多糖,并對其作用機制進行了研究,此外課題組對部分深海微生物和海洋動物的活性成分進行了探索性研究,為海洋創新藥物研發以及海洋生物資源高值化利用做了有益的探索。

    主講人介紹:

        張全斌,中國科學院海洋研究所研究員,博士生導師,兼任中國藻類學會理事,中國海洋湖沼學會藥物學分會理事,中國藻業協會專家委員會委員,中國生物工程學會糖生物工程專業委員會委員,中國生化與分子生物學會糖復合物專業委員會委員。研究方向為海洋藥物,主要聚焦于海洋活性多糖和寡糖的發現、構效關系及作用機制研究以及以海洋多糖/寡糖為基礎的糖類創新藥物及海洋生物資源高值化利用技術研究。對我國海洋生物中的多糖和寡糖進行了系統研究,獲得了1000余個海洋多糖/寡糖及其衍生物;開發了海洋糖類腎病新藥“海昆腎喜膠囊”,并在海洋生物資源高值化利用及新型海洋生物制品研發方面有所突破。先后主持和參加了省部級及以上課題20余項;發表SCI論文88篇,他引約3000次;授權國家發明專利18項;獲省部級科技獎勵3項。


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